WHO Essential · GMP Grade · Pharma API

The world's most
valuable botanical API.

EcoDelta extracts vincristine, vinblastine, vinorelbine, and vindesine from Catharanthus roseus at GMP grade — supplying oncology markets across Europe, the Middle East, and Asia from Africa's botanical heartland.

$1.2M
Per kg vincristine
Peak GMP market price
4
WHO-essential APIs
All extracted by EcoDelta
GMP
Certified extraction
Pharma-grade output
0
Landfill destination
Full biomass utilisation

THE SCIENCE

One flower. Four life-saving medicines.

Madagascar periwinkle (Catharanthus roseus) produces a unique class of monoterpenoid indole alkaloids that disrupt cancer cell division by binding to tubulin — preventing mitosis and triggering apoptosis in malignant cells.

The extraction demands sophisticated chromatographic separation. A kilogram of vincristine requires processing thousands of kilograms of dried plant biomass, making it one of the most labour-intensive and high-value botanical processes in the pharmaceutical industry.

EcoDelta's GMP-certified pipeline handles the full extraction sequence — from raw biomass intake and alkaloid isolation through to purified API, certificate of analysis, and export-ready packaging for global pharma buyers.

Vincristine sulfate
Paediatric ALL, lymphomas, solid tumours
$700,000 – $1,200,000 / kg
WHO Essential
Vinblastine sulfate
Hodgkin lymphoma, testicular cancer, Kaposi sarcoma
$80,000 – $150,000 / kg
WHO Essential
Vinorelbine
Non-small cell lung cancer, metastatic breast cancer
$50,000 – $100,000 / kg
Semi-synthetic
Vindesine
Clinical oncology, paediatric protocols
$40,000 – $80,000 / kg
Clinical Grade
Raw alkaloid extract
Intermediate for further refining
$5,000 – $15,000 / kg
Bulk Supply

EXTRACTION PIPELINE

From field to certified API.

Cam's five-stage vinca alkaloid pipeline — GMP-controlled at every step, with full traceability from biomass intake to export documentation.

01
Biomass intake
Dried Catharanthus roseus leaf graded by alkaloid content, moisture, and contamination screening. Full chain of custody documentation.
02
Solvent extraction
Controlled solvent maceration isolates the crude alkaloid fraction. pH adjustment and liquid-liquid partitioning removes interfering compounds.
03
Chromatographic separation
Column chromatography separates the four primary alkaloids. Ion-exchange and reverse-phase techniques achieve pharmaceutical purity thresholds.
04
Purification & QC
Final recrystallisation and HPLC purity verification. Full CoA issued against BP/USP/EP pharmacopoeia specifications.
05
GMP packaging & export
Cold-chain packaging, SAHPRA export permits, and full documentation for import into EU, UK, US, and Asian pharma markets.

COMPLIANCE & CERTIFICATION

Built to meet global pharma standards.

⚗️
GMP certified
Full pharmaceutical GMP production environment
🏛️
SAHPRA licensed
South African Health Products Regulatory Authority
📋
BP / USP / EP
Certificate of analysis against major pharmacopoeias
🌍
WHO Essential
Vincristine & vinblastine on WHO Essential Medicines List
📦
Cold-chain export
Full cold-chain integrity, EU/UK/US import compliant
🔬
Full traceability
Biomass origin to final API — batch-level documentation

FREQUENTLY ASKED

Common questions from pharma buyers.

What is the minimum order quantity for vincristine API?
Minimum order quantities are negotiated on a per-offtake basis and depend on your production schedule and import permits. Contact engage@ecodelta.biz with your annual volume requirement and we will propose a structured supply agreement.
How do you verify alkaloid purity and issue a CoA?
Every batch undergoes HPLC purity analysis at our GMP-certified laboratory. A full Certificate of Analysis is issued against BP, USP, or EP specifications as required by your market. Third-party laboratory verification can be arranged at buyer's request.
What export documentation is provided?
We provide SAHPRA export permits, phytosanitary certificates, CITES documentation where applicable, full batch records, CoA, and cold-chain shipping documentation. We work with established freight forwarders experienced in controlled pharmaceutical exports.
Can EcoDelta supply raw alkaloid extract for in-house refining?
Yes. We offer crude alkaloid extract as an intermediate product for buyers with their own downstream purification capability. Pricing and specification for crude extract is available on request.
Is biomass sourcing sustainable and traceable?
All Catharanthus roseus biomass is sourced from contracted agricultural partners with full chain-of-custody documentation. We do not use wild-harvested material. Our sourcing model supports rural agricultural income in Southern Africa.
READY TO ENGAGE

Request a vinca alkaloid offtake quote.

Send us your volume requirement, target specification, and destination market and we will respond within 24 hours with a preliminary supply proposal.

Submit RFQ → Email directly